E. Yu. Schmidt, E. V. Ivanova, N. V. Semenova, I. V. Tatarinova, I. A. Ushakov, B. A. Trofimov, “Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles”, Mendeleev Commun., 2015, Volume 25, Issue 2,Pages <nobr>131

This article is cited in 12 papers

Communications

Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles

E. Yu. Schmidt, E. V. Ivanova, N. V. Semenova, I. V. Tatarinova, I. A. Ushakov, B. A. Trofimov

A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, Irkutsk, Russian Federation

Abstract: The sequential reaction of ketones with phenylacetylene in the presence of KOH/DMSO system followed by the treatment of the reaction mixture with HCl and monosubstituted hydrazines leads to pyrazolines and pyrazoles in up to 87% total yield.

Language: English

DOI: 10.1016/j.mencom.2015.03.018

	*Supplementary materials:*
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