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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2015 Volume 25, Issue 2, Pages 138–139 (Mi mendc2327)

This article is cited in 2 papers

Communications

One-pot synthesis of (5-alkyl-1,2,4-oxadiazol-3-yl)benzoic acids

S. V. Baikov, G. G. Krasovskaya, A. V. Kolobov, E. R. Kofanov

Department of Organic Chemistry, Yaroslavl State Technical University, Yaroslavl, Russian Federation

Abstract: Heterocyclization of toluic acid amidoximes with acetic or propionic anhydrides affords 5-alkyl-3-tolyl-1,2,4-oxadiazoles, whose air oxidation in the same vessel gives (5-alkyl-1,2,4-oxadiazol-3-yl)benzoic acids.

Language: English

DOI: 10.1016/j.mencom.2015.03.021



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