I. B. Chernikova, S. L. Khursan, M. S. Yunusov, R. A. Yumagulov, “Chlorination of 5-nitro-6-methyluracil and its N(1),N(3)-dimethyl analogue with molecular chlorine”, Mendeleev Commun., 2015, Volume 25, Issue 3,Pages 221

This article is cited in 5 papers

Communications

Chlorination of 5-nitro-6-methyluracil and its N(1),N(3)-dimethyl analogue with molecular chlorine

I. B. Chernikova^a, S. L. Khursan^a, M. S. Yunusov^a, R. A. Yumagulov^ab

^a Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
^b Department of Chemistry, Bashkir State University, Ufa, Russian Federation

Abstract: The chlorination of 6-methyl-5-nitrouracil with chlorine in methanol results in a two-component mixture of 5-chloro-6-methyl-6-methoxy-5-nitro-5,6-dihydrouracils, while the chlorination of 5-nitro-1,3,6-trimethyluracil under similar conditions gives a mixture of 5-chloro-6-hydroxy-5-nitro-1,3,6-trimethyl-5,6-dihydrouracils. The structures of the chlorination products were suggested based on quantum-chemical calculations

Language: English

DOI: 10.1016/j.mencom.2015.05.022