A. T. Le, H. H. Truong, T. Thi, N. Thi, H. To, H. Thi, A. T. Soldatenkov, “Synthesis and biological activity of (γ-arylpyridino)-dibenzoaza-14-crown-4 ethers”, Mendeleev Commun., 2015, Volume 25, Issue 3,Pages <nobr>224

This article is cited in 21 papers

Communications

Synthesis and biological activity of (γ-arylpyridino)-dibenzoaza-14-crown-4 ethers

A. T. Le^a, H. H. Truong^b, T. Thi^a, N. Thi^a, H. To^c, H. Thi^a, A. T. Soldatenkov^d

^a Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Hoan Kiem, Hanoi, Vietnam
^b Institute of Chemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
^c Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
^d Department of Organic Chemistry, People's Friendship University of Russia, Moscow, Russian Federation

Abstract: Eight novel aza-14-crown-4 compounds incorporating γ-arylpyridine moiety and possessing high inhibitory activity towards cancer cell lines were synthesized in one step from 1,5-bis(2-acetylphenoxy)-3-oxapentane, aromatic aldehyde and ammonium acetate.

Language: English

DOI: 10.1016/j.mencom.2015.05.023