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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2015 Volume 25, Issue 3, Pages 224–225 (Mi mendc2359)

This article is cited in 21 papers

Communications

Synthesis and biological activity of (γ-arylpyridino)-dibenzoaza-14-crown-4 ethers

A. T. Lea, H. H. Truongb, T. Thia, N. Thia, H. Toc, H. Thia, A. T. Soldatenkovd

a Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Hoan Kiem, Hanoi, Vietnam
b Institute of Chemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
c Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
d Department of Organic Chemistry, People's Friendship University of Russia, Moscow, Russian Federation

Abstract: Eight novel aza-14-crown-4 compounds incorporating γ-arylpyridine moiety and possessing high inhibitory activity towards cancer cell lines were synthesized in one step from 1,5-bis(2-acetylphenoxy)-3-oxapentane, aromatic aldehyde and ammonium acetate.

Language: English

DOI: 10.1016/j.mencom.2015.05.023



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