G. V. Pazynina, S. V. Tsygankova, N. V. Bovin, “Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc”, Mendeleev Commun., 2015, Volume 25, Issue 4,Pages <nobr>250

This article is cited in 2 papers

Communications

Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc

G. V. Pazynina, S. V. Tsygankova, N. V. Bovin

M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: Synthesis of Ac₃GlcNAcβ(1-4)-3-Ac-6-BnGlcNTrocβ-O(CH₂)₃NHCOCF₃, a convenient precursor for the preparation of 6-substituted derivatives of disaccharide GlcNAcβ1-4GlcNAc, is described. α-Fucosylation of this precursor after the removal of protection groups leads to the title trisaccharide, whereas O-sulfation results in 6-O-sulfated derivative of chitobiose.

Language: English

DOI: 10.1016/j.mencom.2015.07.004

	*Supplementary materials:*
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