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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2014 Volume 24, Issue 2, Pages 82–84 (Mi mendc2479)

This article is cited in 13 papers

Communications

Guanidine-equipped thiacalix[4]arenes: synthesis, interaction with DNA and aggregation properties

A. V. Galukhina, I. I. Stoikovab

a Alexander Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russian Federation
b Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Centre of the Russian Academy of Sciences, Kazan, Russian Federation

Abstract: New tetrakis-guanidinium-containing p-tert-butylthiacalix[4]arene forms monodisperse nanoparticles with diameter 44nm in the concentration range of 40–100μm. Its association constant with model DNA was evaluated as pKa = 3.96 by fluorescent intercalator displacement assay.

Language: English

DOI: 10.1016/j.mencom.2014.03.005



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