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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2013 Volume 23, Issue 2, Pages 92–93 (Mi mendc2625)

This article is cited in 27 papers

Friedel–Crafts alkylation of natural amino acid-derived pyrroles with CF3-substituted cyclic imines

O. I. Shmatovaa, N. E. Shevchenkoa, E. S. Balenkovaa, G.-V. Roeschenthalerb, V. G. Nenajdenkoa

a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
b School of Engineering and Science, Jacobs University of Bremen, Bremen, Germany

Abstract: Natural amino acid-derived ethyl 2-(1-pyrrolyl)alkanoates react with 2-trifluoromethyl-1-azacycloalkenes selectivity at the b-position of the pyrrole moiety to afford ethyl 2-[3-(1-trifluoromethyl-2-azacycloalkyl)pyrrol-1-yl]alkanoates.

Language: English

DOI: 10.1016/j.mencom.2013.03.013



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