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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2013 Volume 23, Issue 2, Pages 96–97 (Mi mendc2627)

This article is cited in 4 papers

Aldol–Tishchenko–Tishchenko reaction: sodium tert-butoxide-mediated one step formation of 1,3-glycol diester from benzaldehyde and isobutyrophenone

S. Bhowmick, K. Ch. Bhowmick

Department of Chemistry, Visva-Bharati University, Santiniketan, West Bengal, India

Abstract: Sodium tert-butoxide promoted reaction between isobutyrophenone and excess (> 4mol) benzaldehyde gives anti-1,3-dibenzoyloxy- 2,2-dimethyl-1,3-diphenylpropane, a product of sequential aldol–Tishchenko and Tishchenko reactions.

Keywords: 1,3-dibenzoate ester, Aldol-Tishchenko-Tishchenko reaction, diastereoselective synthesis, NaOtBu.

Language: English

DOI: 10.1016/j.mencom.2013.03.015



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