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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2013 Volume 23, Issue 3, Pages 140–141 (Mi mendc2640)

This article is cited in 12 papers

Communications

Synthesis of 6-(arylmethylidene)octahydropyrrolo[1,2-a]pyrimidines and 5-(arylmethylidene)hexahydropyrrolo[1,2-a]imidazoles by the interaction of alk-4-ynals with a,?-diaminoalkanes in DMSO in the presence of KOH

K. N. Shavrin, V. D. Gvozdev, O. M. Nefedov

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: Cyclization of alk-4-ynals with a,?-diaminoalkanes in DMSO under the action of KOH affords bicyclic N,N-enaminals – 6-(aryl- methylidene)octahydro[1,2-a]pyrimidines and 5-(arylmethylidene)hexahydro[1,2-a]imidazoles.

Language: English

DOI: 10.1016/j.mencom.2013.05.006



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