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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2013 Volume 23, Issue 6, Pages 319–320 (Mi mendc2699)

Communications

Difference between conformations of immunoglobulin M and human rheumatoid factor based on small-angle X-ray solution scattering data

V. V. Volkova, V. A. Lapukb, D. I. Chekryginaa, E. Yu. Varlamovac, A. V. Chekushina

a A.V. Shubnikov Institute of Crystallography, FSRC ‘Crystallography and Photonics', Russian Academy of Sciences, Moscow, Russian Federaion
b N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
c Hematology Research Center, Russian Academy of Medical Sciences, Moscow, Russian Federation

Abstract: Radial distribution functions calculated from molecular models point to the difference between conformations of immunoglobulin M and human rheumatoid factor, based on small-angle X-ray solution scattering data.

Keywords: structure of macromolecules, computer simulations, X-ray small-angle scattering, shape determination, immunoglobulin M.

Language: English

DOI: 10.1016/j.mencom.2013.11.004



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