Mendeleev Commun., 2012 Volume 22, Issue 3, Pages 143–144
(Mi mendc2769)
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Non-Catalytic Thermal Multicomponent Assembling of Isatin, Cyclic CH-Acids and Malononitrile: An Efficient Approach to Spirooxindole Scaffold M. N. Elinson a ,
A. I. Ilovaisky a ,
V. M. Merkulova a ,
T. A. Zaimovskaya b ,
G. I. Nikishin a a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation b A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Moscow, Russian Federation Abstract:
Thermal non-catalytic reaction of isatin, cyclic CH-acids and malononitrile in water or alcohols affords substituted spirooxindoles in 90–97% yields.
Language: English
DOI:
10.1016/j.mencom.2012.05.010
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