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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2024 Volume 34, Issue 6, Pages 890–892 (Mi mendc283)

This article is cited in 1 paper

Communications

Cationic glycerolipid as a templating agent for the synthesis of mesoporous silica nanoparticles

O. V. Dement'evaa, E. M. Shishmakovaa, A. V. Ivchenkoa, M. S. Staltsovb, A. A. Markovac, V. M. Rudoya

a A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow, Russian Federation
b National Research Nuclear University MEPhI, Moscow, Russian Federation
c N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: A new method for encapsulating cationic glycerolipids is proposed, based on their use as templating agents in the sol–gel synthesis of mesoporous silica particles. Using the example of rac-N-{4-[(2-ethoxy-3-octadecyloxyprop-1-yl)-oxycarbonyl]butyl}-N’-methylimidazolium iodide, it is shown that this method results in the formation of high-capacity container particles with a pronounced porous structure and a narrow size distribution.

Keywords: mesoporous silica nanoparticles, sol–gel synthesis, glycerolipids, imidazolium salts, liposomes, template, drug delivery.

Language: English

DOI: 10.1016/j.mencom.2024.10.038



© Steklov Math. Inst. of RAS, 2025