O. V. Dement'eva, E. M. Shishmakova, A. V. Ivchenko, M. S. Staltsov, A. A. Markova, V. M. Rudoy, “Cationic glycerolipid as a templating agent for the synthesis of mesoporous silica nanoparticles”, Mendeleev Commun., 2024, Volume 34, Issue 6,Pages <nobr>890

This article is cited in 1 paper

Communications

Cationic glycerolipid as a templating agent for the synthesis of mesoporous silica nanoparticles

O. V. Dement'eva^a, E. M. Shishmakova^a, A. V. Ivchenko^a, M. S. Staltsov^b, A. A. Markova^c, V. M. Rudoy^a

^a A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b National Research Nuclear University MEPhI, Moscow, Russian Federation
^c N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: A new method for encapsulating cationic glycerolipids is proposed, based on their use as templating agents in the sol–gel synthesis of mesoporous silica particles. Using the example of rac-N-{4-[(2-ethoxy-3-octadecyloxyprop-1-yl)-oxycarbonyl]butyl}-N’-methylimidazolium iodide, it is shown that this method results in the formation of high-capacity container particles with a pronounced porous structure and a narrow size distribution.

Keywords: mesoporous silica nanoparticles, sol–gel synthesis, glycerolipids, imidazolium salts, liposomes, template, drug delivery.

Language: English

DOI: 10.1016/j.mencom.2024.10.038