R. N. Khaybullin, I. Yu. Strobykina, V. P. Gubskaya, G. M. Fazleeva, Sh. K. Latypov, V. E. Kataev, “New malonate macrocycle bearing two isosteviol moieties and its adduct with fullerene C<sub>60</sub>”, Mendeleev Commun., 2011, Volume 21, Issue 3,Pages <nobr>134

This article is cited in 11 papers

New malonate macrocycle bearing two isosteviol moieties and its adduct with fullerene C₆₀

R. N. Khaybullin, I. Yu. Strobykina, V. P. Gubskaya, G. M. Fazleeva, Sh. K. Latypov, V. E. Kataev

A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation

Abstract: Macrocycle having two isosteviol moieties and malonate fragment has been synthesised, and its ability to inhibit the growth of Mycobacterium tuberculosis H37Rv in vitro with MIC value of 1mg cm^–3 has been demonstrated. The macrocycle adds fullerene C₆₀ at the activated methylene group to furnish the corresponding methanofullerene conjugate.

Keywords: macrocycles, diterpenoids, isosteviol, beyeran, fullerene.

Language: English

DOI: 10.1016/j.mencom.2011.04.006

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