D. V. Demchuk, M. N. Elinson, G. I. Nikishin, “‘On water’ Knoevenagel condensation of isatins with malononitrile”, Mendeleev Commun., 2011, Volume 21, Issue 4,Pages <nobr>224

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‘On water’ Knoevenagel condensation of isatins with malononitrile

D. V. Demchuk, M. N. Elinson, G. I. Nikishin

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: Grinding of isatins with malononitrile in the presence of 1–5 equiv. of water for 15min at room temperature affords the corresponding (2-oxo-1,2-dihydro-3H-indol-3-ylidene)malononitriles, the Knoevenagel condensation products, in 89–99% yields.

Language: English

DOI: 10.1016/j.mencom.2011.07.018

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