D. V. Vorobyeva, A. S. Bubnova, A. G. Buyanovskaya, S. N. Osipov, “Synthesis of CF3-substituted isoindolones via rhodium(iii)-catalyzed carbenoid C–H functionalization of aryl hydroxamates”, Mendeleev Commun., 2023, Volume 33, Issue 1,Pages 34

This article is cited in 4 papers

Communications

Synthesis of CF₃-substituted isoindolones via rhodium(iii)-catalyzed carbenoid C–H functionalization of aryl hydroxamates

D. V. Vorobyeva, A. S. Bubnova, A. G. Buyanovskaya, S. N. Osipov

A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation

Abstract: An efficient method for the selective preparation of trifluoro-methyl-substituted isoindolones has been developed via Rh^III catalyzed C-H activation / [4 + 1]-annulation of aryl hydroxamates with functionalized acceptor/acceptor diazo compounds as cross-coupling partners.

Keywords: aryl hydroxamates, C-H activation, diazo compounds, rhodium(iii) catalysis, isoindolones, organofluorine compounds.

Language: English

DOI: 10.1016/j.mencom.2023.01.010

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