M. A. Lapitskaya, L. L. Vasiljeva, K. K. Pivnitsky, “Practical synthesis of 16,22-diketocholesterol acetate, a precursor of anticancer saponin OSW-1, from diosgenin”, Mendeleev Commun., 2010, Volume 20, Issue 6,Pages <nobr>318

This article is cited in 2 papers

Practical synthesis of 16,22-diketocholesterol acetate, a precursor of anticancer saponin OSW-1, from diosgenin

M. A. Lapitskaya, L. L. Vasiljeva, K. K. Pivnitsky

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: An improved method using dibromide protection of the 5,6-double bond has been developed for the synthesis of the title compound, which is a key intermediate in the synthesis of saponin OSW-1 from diosgenin.

Language: English

DOI: 10.1016/j.mencom.2010.11.005