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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2010 Volume 20, Issue 6, Pages 321–322 (Mi mendc3079)

This article is cited in 12 papers

A simple synthesis of the lamellarin analogues from 3-nitro-2-trifluoromethyl-2H-chromenes and 1-benzyl-3,4-dihydroisoquinolines

V. Yu. Korotaeva, V. Ya. Sosnovskikha, E. S. Yasnovaa, A. Yu. Barkova, Yu. V. Shklyaevb

a Department of Chemistry, Ural Federal University, Ekaterinburg, Russian Federation
b Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences, Perm, Russian Federation

Abstract: The basic structural framework of lamellarin alkaloids, 8,9-dihydro-6H-chromeno[4’,3’:4,5]pyrrolo[2,1-a]isoquinoline derivatives, was accessed in good yields by the Grob reaction between 3-nitro-2-trifluoromethyl-2H-chromenes and dihydropapaverine or drotaverine in refluxing isobutanol.

Language: English

DOI: 10.1016/j.mencom.2010.11.006



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