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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2009 Volume 19, Issue 3, Pages 152–154 (Mi mendc3151)

This article is cited in 19 papers

Block synthesis of blood group tetrasaccharides B (types 1, 3 and 4)

E. Yu. Korchaginaa, I. M. Ryzhova, K. A. Byrgazova, I. S. Popovaa, S. N. Pokrovskyb, N. V. Bovina

a M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
b Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russian Federation

Abstract: 3-Aminopropyl glycosides of the tetrasaccharides Galα1-3(Fucα1-2)Galβ1-3GlcNAcβ (B type 1), Galα1-3(Fucα1-2)-Galβ1-3GalNAcα (B type 3), and Galα1-3(Fucα1-2)Galβ1-3GalNAcβ (B type 4) were synthesised using acetylated Galα1-3-(Fucα1-2)Gal trichloroacetimidate 4 as a glycosyl donor at the key stage.

Keywords: blood group tetrasaccharides, block synthesis 3+1, aminopropyl glycoside donors.

Language: English

DOI: 10.1016/j.mencom.2009.05.013



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