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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2008 Volume 18, Issue 2, Pages 109–111 (Mi mendc3266)

This article is cited in 9 papers

Synthesis of 4-haloquinolines and their fused polycyclic derivatives

M. S. Shvartsberg, E. A. Kolodina

V.V. Voevodsky Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation

Abstract: A general method for the synthesis of 4-chloro- or 4-bromo-substituted quinolines and quinoline moieties of polycyclic compounds includes the addition of hydrogen halides to vic-amino(3-oxoalk-1-ynyl)arenes under mild conditions followed by the intramolecular cyclization of the adducts.

Language: English

DOI: 10.1016/j.mencom.2008.03.020



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