A. S. Kozlov, O. I. Afanasyev, M. A. Losev, M. I. Godovikova, D. Chusov, “Nitrogen ligand influence on the CO-assisted ruthenium-catalyzed reductive amination”, Mendeleev Commun., 2023, Volume 33, Issue 2,Pages <nobr>174

Communications

Nitrogen ligand influence on the CO-assisted ruthenium-catalyzed reductive amination

A. S. Kozlov^a, O. I. Afanasyev^a, M. A. Losev^ab, M. I. Godovikova^a, D. Chusov^ac

^a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^b National Research University Higher School of Economics (HSE University), Moscow, Russian Federation
^c G.V. Plekhanov Russian University of Economics, Moscow, Russian Federation

Abstract: A representative set of amines and N-heterocycles was applied as additives in the CO-assisted Ru-catalyzed reductive amination of p-anisaldehyde with p-anisidine. Among the tested ligands, pyridine caused a strong activation for low active aliphatic substrates while bidentate heterocyclic ligands possess significant inhibition of catalyst for the majority of substrates.

Keywords: ruthenium, nitrogen-containing ligands, reductive amination, amines, aldehydes, carbon monoxide, catalysis.

Language: English

DOI: 10.1016/j.mencom.2023.02.008

	*Supplementary materials:*
		Supplementary_data_1.pdf	829.2 Kb