A. V. Nemukhin, I. A. Gariev, A. V. Rogov, S. D. Varfolomeev, “Serine hydrolase catalytic sites : geometry invariants and modeling catalytic activity”, Mendeleev Commun., 2006, Volume 16, Issue 6,Pages <nobr>290

This article is cited in 10 papers

Serine hydrolase catalytic sites : geometry invariants and modeling catalytic activity

A. V. Nemukhin^ab, I. A. Gariev^a, A. V. Rogov^b, S. D. Varfolomeev^ab

^a N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russian Federation
^b Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: An analysis of the catalytic site structures and quantum mechanical – molecular mechanical modeling of the reaction mechanism of serine hydrolases provide direct credentials to the Koshland's induced fit concept of enzymatic catalysis.

Language: English

DOI: 10.1070/MC2006v016n06ABEH002418