R. R. Nagawade, S. A. Kotharkar, D. B. Shinde, “Titanium(IV) chloride catalyzed one-pot synthesis of 3,4-dihydropyrimidin- 2(1<i>H</i>)-ones and thiones”, Mendeleev Commun., 2005, Volume 15, Issue 4,Pages <nobr>150

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Titanium(IV) chloride catalyzed one-pot synthesis of 3,4-dihydropyrimidin- 2(1H)-ones and thiones

R. R. Nagawade^a, S. A. Kotharkar^b, D. B. Shinde^b

^a Wockhardt Research Centre, Aurangabad, India
^b Department of Chemical Technology, Dr. B.A. Marathwada University, Aurangabad, India

Abstract: Titanium(IV) chloride catalyses efficiently the three-component condensation reaction of an aldehyde, 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones and thiones in high yields.

Language: English

DOI: 10.1070/MC2005v015n04ABEH002123