S. V. Bureeva, J. E. Andia-Pravdivy, A. M. Bichucher, D. A. Orishchenko, A. P. Kaplun, “QSAR of inhibition of classical pathway of complement activation by dicarboxylic acids”, Mendeleev Commun., 2005, Volume 15, Issue 6,Pages <nobr>253

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QSAR of inhibition of classical pathway of complement activation by dicarboxylic acids

S. V. Bureeva^a, J. E. Andia-Pravdivy^a, A. M. Bichucher^b, D. A. Orishchenko^a, A. P. Kaplun^a

^a M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation
^b G.N. Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, Russian Federation

Abstract: The influence of distance between charges, hydrophobic and electronic parameters of aliphatic and aromatic dicarboxylic acids on the complement-inhibiting activity (CIA) has been ascertained using the QSAR method.

Language: English

DOI: 10.1070/MC2005v015n06ABEH002143