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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2004 Volume 14, Issue 6, Pages 249–250 (Mi mendc3898)

This article is cited in 36 papers

Asymmetric synthesis of cyanohydrins catalysed by a potassium Δ-bis[N-salicylidene-(R)-tryptophanato]cobaltate complex

Yu. N. Belokona, A. G. Bulychevb, V. I. Maleeva, M. Northc, I. L. Malfanovb, N. S. Ikonnikova

a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
b Department of Chemistry, Kaliningrad State University, Kaliningrad, Russian Federation
c School of Natural Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom

Abstract: A chiral cobalt(III) complex of a Schiff base derived from (R)-tryptophan and salicylaldehyde catalysed asymmetric trimethyl-silylcyanation of benzaldehyde at ambient temperature and a 20:1 substrate/catalyst ratio with the formation of enantiomerically enriched mandelonitrile (ee up to 77%).

Language: English

DOI: 10.1070/MC2004v014n06ABEH002029



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