A. S. Efimova, M. A. Ustimova, M. A. Maksimova, A. Yu. Frolova, V. I. Martynov, S. M. Deyev, A. A. Pakhomov, Yu. V. Fedorov, O. A. Fedorova, “Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody”, Mendeleev Commun., 2023, Volume 33, Issue 3,Pages <nobr>384–386</nobr>

RUS ENG

JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2023 Volume 33, Issue 3, Pages 384–386 (Mi mendc404)

This article is cited in 6 papers

Communications

Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody

A. S. Efimova^ab, M. A. Ustimova^a, M. A. Maksimova^acd, A. Yu. Frolova^ac, V. I. Martynov^c, S. M. Deyev^c, A. A. Pakhomov^ac, Yu. V. Fedorov^a, O. A. Fedorova^ab

^a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
^c M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^d Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: Two new styryl-type dyes modified with the succinimide ester group were prepared for conjugation with antibodies. The optical characteristics of the obtained compounds in different solvents were studied, and the solvatochromic properties of these dyes were revealed. The applicability of the dyes as protein labels was demonstrated in cyto-fluorometry and fluorescence microscopy.

Keywords: fluorescent probes, covalent labeling, antibody, protein, styryl dyes, pyridinium salts.

Language: English

DOI: 10.1016/j.mencom.2023.04.027

Fulltext: PDF file (543 kB)
Cited by

	*Supplementary materials:*
		Supplementary_data_1.pdf	2.6 Mb

© Steklov Math. Inst. of RAS, 2025