K. V. Alferov, N. G. Faleev, E. N. Khurs, Yu. N. Zhukov, R. M. Khomutov, “A phosphinic analogue of methionine is a substrate of L-methionine-γ-lyase and induces the synthesis of the enzyme in <i>Citrobacter intermedius</i> cells”, Mendeleev Commun., 2002, Volume 12, Issue 1,Pages <nobr>2

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A phosphinic analogue of methionine is a substrate of L-methionine-γ-lyase and induces the synthesis of the enzyme in Citrobacter intermedius cells

K. V. Alferov^a, N. G. Faleev^b, E. N. Khurs^a, Yu. N. Zhukov^a, R. M. Khomutov^a

^a V.A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russian Federation
^b A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation

Abstract: 1-Amino-3-(methylthio)propylphosphinic acid likewise methionine, is a substrate in α,γ-elimination and γ-substitution reactions catalysed by pyridoxal-5’-phosphate-dependent L-methionine-γ-lyase and is capable to induce the synthesis of this enzyme in Citrobacter intermedius cells as does L-methionine.

Language: English

DOI: 10.1070/MC2002v012n01ABEH001550