R. G. Kostyanovsky, G. K. Kadorkina, K. A. Lyssenko, V. Yu. Torbeev, A. N. Kravchenko, O. V. Lebedev, G. V. Grintselev-Knyazev, V. R. Kostyanovsky, “Chiral drugs <i>via</i> the spontaneous resolution”, Mendeleev Commun., 2002, Volume 12, Issue 1,Pages <nobr>6–8</nobr>

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Mendeleev Commun., 2002 Volume 12, Issue 1, Pages 6–8 (Mi mendc4066)

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Chiral drugs via the spontaneous resolution

R. G. Kostyanovsky^a, G. K. Kadorkina^a, K. A. Lyssenko^b, V. Yu. Torbeev^a, A. N. Kravchenko^c, O. V. Lebedev^c, G. V. Grintselev-Knyazev^b, V. R. Kostyanovsky^a

^a N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Moscow, Russian Federation
^b A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^c N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: The psychotropically active drug Albicar 1 has been prepared for the first time in both enantiomerically pure forms starting from the (+)-2 and (–)-2 precursors obtained by spontaneous resolution; the crystal structures of (–)-1 and (±)-1 have been solved by X-ray diffraction study.

Language: English

DOI: 10.1070/MC2002v012n01ABEH001521

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