K. E. Polunin, I. A. Polunina, H. G. Schmalz, “η6-Arene–tricarbonylchromium complexes in the syntheses of trans-resveratrol and pinostilbene”, Mendeleev Commun., 2002, Volume 12, Issue 5,Pages 178

This article is cited in 9 papers

η⁶-Arene–tricarbonylchromium complexes in the syntheses of trans-resveratrol and pinostilbene

K. E. Polunin^a, I. A. Polunina^a, H. G. Schmalz^b

^a Institute of Physical Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b Institute of Organic Chemistry, University of Cologne, Koeln, Germany

Abstract: New syntheses of trans-resveratrol (trans-3,5,4’-trihydroxystilbene) and pinostilbene (trans-3,4’-dihydroxy-5-methoxystilbene) via nucleophilic demethylation of trimethoxystilbene were performed, whereby trans-3,5,4’-trimethoxystilbene was obtained through facilitated benzylic deprotonation of an η⁶-benzene-Cr(CO)₃ derivative and subsequent coupling with para-anisaldehyde in an aldol-type or Wittig–Horner reaction.

Language: English

DOI: 10.1070/MC2002v012n05ABEH001616