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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2001 Volume 11, Issue 2, Pages 82–83 (Mi mendc4229)

This article is cited in 2 papers

Cyclization of 5-(2-chloroethoxy)-1,5-dihydro-2H-pyrrol-2-ones

K. V. Nikitina, N. P. Andryukhovaa, E. K. Ryub

a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
b Bioorganic Science Division, Korean Research Institute of Chemical Technology, Taejon, Korea

Abstract: The intramolecular cyclization of substituted 5-(2-chloroethoxy)-1,5-dihydro-2H-pyrrol-2-ones in the presence of lithium diisopropylamide hexamethylphosphoramide in tetrahydrofuran gave tetrahydropyrano[2,3-b]pyrrol-6(2H)-ones and 3,4-dihydro-2H-pyrrolo-[2,1-b][1,3]oxazin-6(8aH)-ones in moderate to good yields.

Language: English

DOI: 10.1070/MC2001v011n02ABEH001390



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