Yu. A. Azev, S. V. Shorshnev, D. Gabel, “Stable σ-adducts of 5-azauracil with C-nucleophiles”, Mendeleev Commun., 2001, Volume 11, Issue 6,Pages <nobr>234

This article is cited in 4 papers

Stable σ-adducts of 5-azauracil with C-nucleophiles

Yu. A. Azev^a, S. V. Shorshnev^b, D. Gabel^c

^a Ural Scientific Research Institute of Technology of Medical Preparations, Ekaterinburg, Russian Federation
^b ChemBridge, Moscow, Russian Federation
^c Department of Chemistry, University of Bremen, Bremen, Germany

Abstract: The heating of 5-azauracil 1 with malonamide in butanol resulted in 1,2,3,4,5,6-hexahydro-6-(dicarbamoylmethyl)-1,3,5-triazine- 2,4-dione 3. Under conditions of acid catalysis, compound 1 reacted with o-phenylenediamine, pyrrogallol, resorcinol and phenylhydrazine derivatives to form the corresponding 6-derivatives of 1,2,3,4,5,6-hexahydro-1,3,5-triazine-2,4-dione.

Language: English

DOI: 10.1070/MC2001v011n06ABEH001508