I. V. Lavrentev, K. E. Shepelenko, I. G. Gnatiuk, A. A. Aleksandrov, Y. Zhang, V. M. Chernyshev, “CH-alkylation of furan derivatives under photoinduced Pd catalysis”, Mendeleev Commun., 2023, Volume 33, Issue 4,Pages <nobr>494

This article is cited in 5 papers

Communications

CH-alkylation of furan derivatives under photoinduced Pd catalysis

I. V. Lavrentev^a, K. E. Shepelenko^a, I. G. Gnatiuk^a, A. A. Aleksandrov^a, Y. Zhang^b, V. M. Chernyshev^a

^a Platov South-Russian State Polytechnic University, Novocherkassk, Russian Federation
^b Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, Guangzhou, China

Abstract: A new method for selective C(5)–H alkylation of 2-substituted furans with tertiary and secondary alkyl bromides under photoinduced by visible light (∼460 nm) palladium catalysis has been developed. The method is relied on the use of available Pd(PPh₃)₄ catalyst under mild conditions (30 ± 5 °C, K₂CO₃ as base), tolerates to various functional groups in furanic substrates and provides from good to excellent yields of alkylated products.

Keywords: furan, CH-alkylation, palladium, photoinduced metal catalysis, 2-hetarylfurans.

Language: English

DOI: 10.1016/j.mencom.2023.06.017

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