A. A. Antonets, K. M. Voroshilkina, I. A. Shutkov, D. M. Mazur, V. Yu. Tyurin, L. G. Dubova, E. F. Shevtsova, A. A. Nazarov, E. R. Milaeva, “RuII and RuIII complexes with 2,6-di-tert-butylphenol ligands: synthesis, electrochemical behaviour, antioxidant properties and antiproliferative activity”, Mendeleev Commun., 2024, Volume 34, Issue 1,Pages 74

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Communications

Ru^II and Ru^III complexes with 2,6-di-tert-butylphenol ligands: synthesis, electrochemical behaviour, antioxidant properties and antiproliferative activity

A. A. Antonets^a, K. M. Voroshilkina^a, I. A. Shutkov^a, D. M. Mazur^a, V. Yu. Tyurin^a, L. G. Dubova^b, E. F. Shevtsova^b, A. A. Nazarov^a, E. R. Milaeva^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation

Abstract: New ruthenium(ii) and ruthenium(iii) complexes with 2,6-di-tert-butylphenol as the antioxidant moiety were synthesized, and their antioxidant and antiproliferative activities were evaluated. Electrochemical behaviour and the potential of these compounds to act as inhibitors of lipid peroxidation in biological systems were explored.

Keywords: ruthenium compounds, antioxidant activity, DPPH assay, CUPRAC assay, electrochemical behaviour, antiproliferative activity, lipid peroxidation.

Language: English

DOI: 10.1016/j.mencom.2024.01.022

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