P. M. Demin, T. A. Manukina, C. R. Pace-Asciak, K. K. Pivnitsky, “Total synthesis of 20-hydroxy-hepoxilins, new metabolites of the hepoxilin family”, Mendeleev Commun., 1996, Volume 6, Issue 4,Pages <nobr>130

This article is cited in 7 papers

Total synthesis of 20-hydroxy-hepoxilins, new metabolites of the hepoxilin family

P. M. Demin^a, T. A. Manukina^a, C. R. Pace-Asciak^b, K. K. Pivnitsky^c

^a Institute of Experimental Endocrinology of the National Endocrinology Scientific Centre, Russian Academy of Medical Sciences, Moscow
^b Research Institute, Hospital for Sick Children, Toronto, ON Canada
^c N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: A newly described enzymatically formed ω-hydroxy metabolite of hepoxilin A₃ (HxA₃) has been prepared via total synthesis involving polyacetylenic intermediates and Mitsunobu rearrangement of the intermediate putative ω-hydroxy metabolite of hepoxilin B₃.

Language: English

DOI: 10.1070/MC1996v006n04ABEH000613