E. A. Mistryukov, O. N. Sorokina, A. E. Mistryukov, “Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines”, Mendeleev Commun., 1996, Volume 6, Issue 6,Pages <nobr>39

This article is cited in 3 papers

Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines

E. A. Mistryukov^a, O. N. Sorokina^a, A. E. Mistryukov^b

^a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b N.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: The efficient Lewis acid assisted cyclisation of β-phenylethylamide into dihydroisoquinolines was optimised in relation to metal chloride catalyst, and by X-ray crystallography a new type of non-bonded interaction in the cyclic systems was demonstrated: face coordination of the Cl-anion and an electron deficient pyridinium π-system.

Language: English

DOI: 10.1070/MC1996v006n06ABEH000741