M. Bordoloi, G. M. Singhal, N. B. Das, R. P. Sharma, “Stannous lodide–HCI in Tetrahydrofuran: A New System for the Reduction of various Nitro Compounds. Mild Conversion of 6-Nitro-Δ<sup>5</sup>-Steroids to 6-Keto-steroids”, Mendeleev Commun., 1994, Volume 4, Issue 2,Pages <nobr>62

This article is cited in 2 papers

Stannous lodide–HCI in Tetrahydrofuran: A New System for the Reduction of various Nitro Compounds. Mild Conversion of 6-Nitro-Δ⁵-Steroids to 6-Keto-steroids

M. Bordoloi^a, G. M. Singhal^b, N. B. Das^c, R. P. Sharma^d

^a Natural Products Chemistry Group, Regional Research Laboratory, Assam, India
^b Atul Chemicals, Valsad, Gujrat, India
^c RRL Bhubaneswar, Bhubaneswar, Orissa, India
^d Phytochemistry Division, CIMAP, Lucknow, India

Abstract: It has been shown that 6-nitro-Δ⁵-steroids, nitrostyrene and saturated aliphatic nitro compounds in tetrahydrofuran are reduced efficiently with stannous iodide and a catalytic amount of concentrated hydrochloric acid to the corresponding 6-ketosteroids, oximes or hydroxylamine derivatives in good yields, respectively.

Language: English

DOI: 10.1070/MC1994v004n02ABEH000350