Ya.-J. Fan, D. Wang, L. Wang, Y. Zhou, “Synthesis of propargylamines catalyzed by <i>in situ</i> generated copper nanoparticles in water”, Mendeleev Commun., 2023, Volume 33, Issue 6,Pages <nobr>829

This article is cited in 2 papers

Communications

Synthesis of propargylamines catalyzed by in situ generated copper nanoparticles in water

Ya.-J. Fan^a, D. Wang^a, L. Wang^a, Y. Zhou^b

^a School of Chemical and Pharmaceutical Engineering, Changzhou Vocational Institute of Engineering, Changzhou, P.R. China
^b School of Petrochemical Engineering, Changzhou University, Changzhou, China

Abstract: An efficient and green protocol for the A³ coupling reaction of aldehyde, amine and alkyne involves the use of copper nanoparticles and β-cyclodextrin in water. The copper nanoparticles are generated in situ by reduction with green and cheap sodium hydroxymethanesulfinate (rongalite) while β-cyclodextrin serves as a stabilizing agent and a phase-transfer catalyst.

Keywords: A³ coupling reaction, copper nanoparticles, propargylamines, rongalite, β-cyclodextrin, Mannich reaction.

Language: English

DOI: 10.1016/j.mencom.2023.10.030

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