E. V. Dovgilevich, I. A. Parshikov, L. V. Modyanova, P. B. Terentiev, G. A. Bulakhov, “A Novel Microbial Transformation of -γ-Carboline Derivative 3,6-Dimethyl-9-[2-(2-methylpyrid-5-yl)ethyl]-1,2,3,4-tetrahydro-γ-carboline”, Mendeleev Commun., 1991, Volume 1, Issue 2,Pages <nobr>42

This article is cited in 3 papers

A Novel Microbial Transformation of -γ-Carboline Derivative 3,6-Dimethyl-9-[2-(2-methylpyrid-5-yl)ethyl]-1,2,3,4-tetrahydro-γ-carboline

E. V. Dovgilevich, I. A. Parshikov, L. V. Modyanova, P. B. Terentiev, G. A. Bulakhov

Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: The transformation of ‘Dimebon’, a γ-carboline derivative, has been accomplished by Penicillium simplicissimum and involves dehydrogenation of the γ-carboline ring, followed by N-demethylation, formation of a carbonyl group at C-4 and N-acetylation.

Language: English

DOI: 10.1070/MC1991v001n02ABEH000024