A. V. Gulevskaya, A. F. Pozharskii, S. V. Shorshnev, V. V. Kuz'menko, “Different Behaviour of Fervenulin 4-Oxide and 1,3-Dimethyllumazine 5-Oxide towards Nucleophiles”, Mendeleev Commun., 1991, Volume 1, Issue 2,Pages <nobr>46

This article is cited in 6 papers

Different Behaviour of Fervenulin 4-Oxide and 1,3-Dimethyllumazine 5-Oxide towards Nucleophiles

A. V. Gulevskaya^a, A. F. Pozharskii^a, S. V. Shorshnev^b, V. V. Kuz'menko^c

^a Department of Chemistry, Southern Federal University, Rostov-on-Don, Russian Federation
^b Ural Scientific Research Institute of Technology of Medical Preparations, Ekaterinburg, Russian Federation
^c Southern Federal University, Rostov-on-Don, Russian Federation

Abstract: Fervenulin 4-oxide reacts with secondary amines and carbanions to give derivatives of 1,3-dimethyl-5-nitroso-6-hydrazinouracil 9 and 10; under similar conditions 1,3-dimethyllumazine 5-oxide reacts with piperidine and morpholine to give products 14 in high yield, by nucleophilic substitution of hydrogen at C(6).

Language: English

DOI: 10.1070/MC1991v001n02ABEH000026