S. V. Kurmaz, N. V. Fadeeva, J. A. Skripets, R. I. Komendant, V. M. Ignatiev, N. S. Emelyanova, J. V. Soldatova, I. I. Faingold, D. A. Poletaeva, R. A. Kotelnikova, “New water-soluble forms of α-tocopherol: preparation and study of antioxidant activity <i>in vitro</i>”, Mendeleev Commun., 2022, Volume 32, Issue 1,Pages <nobr>117

This article is cited in 7 papers

Communications

New water-soluble forms of α-tocopherol: preparation and study of antioxidant activity in vitro

S. V. Kurmaz^a, N. V. Fadeeva^a, J. A. Skripets^b, R. I. Komendant^a, V. M. Ignatiev^ab, N. S. Emelyanova^a, J. V. Soldatova^a, I. I. Faingold^a, D. A. Poletaeva^a, R. A. Kotelnikova^a

^a Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
^b Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: Water-soluble forms of α-tocopherol (vitamin E) possessing antioxidant activity in vitro were obtained by encapsulating in N-vinylpyrrolidone with triethylene glycol dimethacrylate polymer particles and were characterized by various physicochemical methods. Quantum-chemical modeling of a structure of α-tocopherol with the copolymer moiety and its theoretical absorption spectra modeling were carried out.

Keywords: N-vinylpyrrolidone, triethylene glycol dimethacrylate, amphiphilic copolymer, α-tocopherol, encapsulation, antioxidant activity.

Language: English

DOI: 10.1016/j.mencom.2022.01.038

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