R. R. Davletshin, A. M. Gayneev, E. A. Ermakova, N. V. Davletshina, I. V. Galkina, K. A. Ivshin, M. P. Shulaeva, O. K. Pozdeev, “Biological activity of new amino phospha betaines with C10–C18 alkyl groups”, Mendeleev Commun., 2022, Volume 32, Issue 2,Pages <nobr>180

This article is cited in 16 papers

Communications

Biological activity of new amino phospha betaines with C10–C18 alkyl groups

R. R. Davletshin^a, A. M. Gayneev^a, E. A. Ermakova^a, N. V. Davletshina^a, I. V. Galkina^a, K. A. Ivshin^a, M. P. Shulaeva^b, O. K. Pozdeev^b

^a A.M. Butlerov Chemistry Institute, Kazan Federal University, Kazan, Russian Federation
^b Kazan State Medical University, Kazan, Russian Federation

Abstract: New amino phospha betaines were obtained by quaternization of potassium salt of amino phosphonate and higher alkyl bromides. The structure of isopropyl (N-dodecyl-N,N- dimethylammoniomethyl)phosphonate was confirmed by single crystal X-ray diffraction. All synthesized compounds demonstrate high antibacterial and antifungal activities.

Keywords: betaines, organophosphorus compounds, quaternary ammonium salts, amino phosphonates, antimicrobial activity, antifungal activity, X-ray diffraction.

Language: English

DOI: 10.1016/j.mencom.2022.03.009

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