A. A. Fateeva, I. A. Shutkov, D. M. Mazur, O. N. Kovaleva, E. R. Milaeva, A. A. Nazarov, “RuII and RuIII complexes with imidazole ligands containing (benzyloxy)pyridinone moiety”, Mendeleev Commun., 2022, Volume 32, Issue 2,Pages 186

This article is cited in 2 papers

Communications

Ru^II and Ru^III complexes with imidazole ligands containing (benzyloxy)pyridinone moiety

A. A. Fateeva^a, I. A. Shutkov^a, D. M. Mazur^a, O. N. Kovaleva^b, E. R. Milaeva^a, A. A. Nazarov^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation

Abstract: Preparation of novel imidazole ligands containing 3-(benzyloxy)pyridinone moiety is described. The Ruiii and Ruii leader-compounds containing the above-mentioned ligands were synthesized by coordination of imidazole group. The stability of the obtained compounds was explored in buffer solution and in the presence of DMSO, respectively, and their antiproliferative activity was assessed.

Keywords: pyridinone, imidazoles, ruthenium compounds, stability, antiproliferative activity.

Language: English

DOI: 10.1016/j.mencom.2022.03.011

	*Supplementary materials:*
		Supplementary_data_1.pdf	1.8 Mb