V. K. Dolgova, A. V. Gopin, A. L. Nikolaev, A. P. Orlov, T. P. Trofimova, M. A. Orlova, “Enzymatic hydroxyapatite as a carrier for yttrium-90 and copper and ruthenium radionuclides”, Mendeleev Commun., 2022, Volume 32, Issue 2,Pages <nobr>281

This article is cited in 5 papers

Communications

Enzymatic hydroxyapatite as a carrier for yttrium-90 and copper and ruthenium radionuclides

V. K. Dolgova^a, A. V. Gopin^a, A. L. Nikolaev^a, A. P. Orlov^a, T. P. Trofimova^ab, M. A. Orlova^ac

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
^c N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation

Abstract: The use of hydroxyapatite obtained by enzymatic synthesis (HAP_E) as a carrier of radionuclides (yttrium-90, copper(II) as a prototype of ⁶⁴Cu and ⁶⁷Cu and ruthenium-103 as a prototype of ⁹⁷Ru) is considered. The processes of sorption and desorption of ions in different solutions are compared. The sorption of copper and yttrium on HAP_E is almost irreversible, in contrast to the sorption of ruthenium, for which the reverse process depends on the medium.

Keywords: hydroxyapatite, alkaline phosphatase, ¹⁰³Ru, ⁹⁰Y, copper ions, sorption, desorption, sorption isotherms.

Language: English

DOI: 10.1016/j.mencom.2022.03.043

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