D. O. Antuganov, M. A. Nadporojskii, Yu. A. Kondratenko, “Al[<sup>18</sup>F]F-HBED-CC-radiolabeling in a media of protic alkanolammonium ionic liquids”, Mendeleev Commun., 2022, Volume 32, Issue 3,Pages <nobr>408

This article is cited in 7 papers

Communications

Al[¹⁸F]F-HBED-CC-radiolabeling in a media of protic alkanolammonium ionic liquids

D. O. Antuganov^a, M. A. Nadporojskii^a, Yu. A. Kondratenko^b

^a A.M. Granov Russian Research Center for Radiology and Surgical Technologies, St. Petersburg, Russian Federation
^b I.V. Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences, St. Petersburg, Russian Federation

Abstract: The possibility of Al¹⁸F-radiolabeling of molecules with the N,N'-bis[2-hydroxy-5-(2-carboxyethyl)benzyl]ethylenediamine-N, N'-diacetic acid motif in the medium of protic alkanolammonium ionic liquids is reported for the first time. Ionic liquids containing triethanolammonium or triisopropanolammonium cations proved to be the most promising. High values of radiochemical conversion were achieved using the minimum amount of the precursor.

Keywords: protic ionic liquids, Al¹⁸F-radiolabeling, positron emission tomography, fluorine-18, radiopharmaceutical.

Language: English

DOI: 10.1016/j.mencom.2022.05.040

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