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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2022 Volume 32, Issue 4, Pages 549–550 (Mi mendc722)

This article is cited in 2 papers

Communications

Reaction of 2-azabicyclo[2.2.1]heptenes with nitrile oxides

T. A. Solodovnikova, N. V. Zyk, A. Yu. Gavrilova

Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: The reaction of 2-azanorbornene derivatives with nitrile oxides (generated in situ by dehydrohalogenation of N-hydroxyimoyl halides) affords two regioisomers with the exo-arrangement of the isoxazoline ring.

Keywords: 2-azabicyclo[2.2.1]heptanes, nitrile oxides, 13-dipolar cycloaddition, hydroxyimoyl halides, norbornene, isoxazolines.

Language: English

DOI: 10.1016/j.mencom.2022.07.038



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