Abstract:
Pyrrolo[1,2-b]pyridazines continue to attract significant interest due to their diverse biological activities. This review explores various synthetic approaches to constructing the pyrrolo[1,2-b]pyridazine scaffold and examines its applications. Covering key advancements in pyrrolo[1,2-b]pyridazine chemistry reported between 2008 and 2024, we highlight their role in the development of practically relevant compounds. By emphasizing recent progress in this field, we aim to inspire further research and innovation in the synthesis and application of these heterocyclic systems.