S. A. Krasnova, A. Yu. Smirnov, M. S. Baranov, D. S. Ivanov, “Photochemical synthesis of benzo[<em>d</em>]imidazole-4-carboxylic acids from 3-(dialkylamino)-2-nitrobenzaldehydes”, Mendeleev Commun., Mi mendc7461

Communications

Photochemical synthesis of benzo[d]imidazole-4-carboxylic acids from 3-(dialkylamino)-2-nitrobenzaldehydes

S. A. Krasnova^a, A. Yu. Smirnov^ab, M. S. Baranov^ab, D. S. Ivanov^a

^a M. M. Shemyakin–Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russian Federation
^b N. I. Pirogov Russian National Research Medical University, 117997 Moscow, Russian Federation

Abstract: Photochemical method for synthesizing benzo[d]imidazole 4-carboxylic acids via 365 nm irradiation of 3-(dialkylamino) 2-nitrobenzaldehydes is presented. The reaction proceeds in high yields (72–98%).

Keywords: ortho-substituted benzaldehydes, 3-(dialkylamino)-2-nitrobenzaldehydes, benzo[d]imidazole-4-carboxylic acids, photochemical cyclization.

Received: 24.11.2025
Accepted: 04.02.2026

Language: English

DOI: 10.71267/mencom.7974