L. Wang, Sh. Qiu, Dan Wang, M. Hong, “FeCl<sub>3</sub>/HCl-photocatalyzed synthesis of benzylidenebarbituric acids from methylarenes”, Mendeleev Commun., Mi mendc7477

Communications

FeCl₃/HCl-photocatalyzed synthesis of benzylidenebarbituric acids from methylarenes

L. Wang^a, Sh. Qiu^a, Dan Wang^a, M. Hong^b

^a School of Chemical and Pharmaceutical Engineering, Changzhou Vocational Institute of Engineering, 213164 Changzhou, P. R. China
^b College of Chemical Engineering, Nanjing Forestry University, 210037 Nanjing, P. R. China

Abstract: FeCl₃/HCl was identified as a simple and robust bifunctional catalytic system for the one-pot synthesis of benzylidenebarbituric acids from methylarenes and barbituric acids. This transformation involved the photocatalyzed selective oxidation of methylarenes to the corresponding benzaldehydes followed by the Knoevenagel condensation with barbituric acid.

Keywords: photocatalysis, selective oxidation, Knoevenagel condensation, iron trichloride, methylarenes, benzylidenebarbituric acids, barbituric acids.

Received: 26.01.2026
Accepted: 28.02.2026

Language: English

DOI: 10.71267/mencom.8003