D. R. Bazanov, V. Yu. Savitskaya, N. A. Maximova, V. Yu. Tyurin, Yu. A. Gracheva, N. B. Chesnokova, O. V. Beznos, S. E. Sosonyuk, N. A. Lozinskaya, “Antioxidant activity and redox properties of <i>cis</i>-2,4,5-tris(hydroxyaryl)imidazolines”, Mendeleev Commun., 2022, Volume 32, Issue 5,Pages <nobr>680

This article is cited in 2 papers

Communications

Antioxidant activity and redox properties of cis-2,4,5-tris(hydroxyaryl)imidazolines

D. R. Bazanov^a, V. Yu. Savitskaya^a, N. A. Maximova^a, V. Yu. Tyurin^a, Yu. A. Gracheva^a, N. B. Chesnokova^b, O. V. Beznos^b, S. E. Sosonyuk^a, N. A. Lozinskaya^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Helmholtz National Medical Centre of Eye Diseases, Moscow, Russian Federation

Abstract: New effective antioxidants of cis-2,4,5-tris(hydroxyaryl)imidazoline type were assembled from aromatic aldehydes and ammonia. Their antioxidant activity was measured against hydroxyl radical and superoxide radical anion in physiological media, and oxidation potentials were measured by cyclic voltammetry. The lead compound bearing 3,4,5-hydroxyphenyl moieties showed activity 3.5 times higher compared to Trolox.

Keywords: phenolic antioxidants, cis-imidazolines, polyphenolic compounds, quinonoid oxidation, propyl gallate, superoxide anion, ionol analogues.

Language: English

DOI: 10.1016/j.mencom.2022.09.038

	*Supplementary materials:*
		Supplementary_data_1.pdf	887.1 Kb