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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2022 Volume 32, Issue 6, Pages 810–812 (Mi mendc807)

This article is cited in 8 papers

Communications

Osteoconductive biocompatible 3D-printed composites of poly-d,l-lactide filled with nanocrystalline cellulose modified by poly(glutamic acid)

I. V. Averianova, M. A. Stepanovaa, I. V. Gofmana, A. Lavrentievab, V. A. Korzhikov-Vlakhc, E. G. Korzhikova-Vlakhac

a Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russian Federation
b Institute of Technical Chemistry, Leibniz University of Hannover, Hannover, Germany
c Institute of Chemistry, St. Petersburg State University, St. Petersburg, Russian Federation

Abstract: Three dimensional composite matrices based on poly-d,l-lactide filled with 5 or 10 wt% of nanocrystalline cellulose modified by poly(glutamic acid) were produced using pre- optimized 3D printing technique. The composites demonstrated good biocompatibility and significantly improved osteoconductive properties compared with the matrix without filler or the one filled with neat nanocrystalline cellulose.

Keywords: poly-d,l-lactide, modified nanocrystalline cellulose, poly(glutamic acid), composite three dimensional matrix, 3D printing, osteoconductive material, biomineralization, bone regeneration.

Language: English

DOI: 10.1016/j.mencom.2022.11.034



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