K. N. Sedenkova, D. A. Vasilenko, D. V. Zverev, K. S. Sadovnikov, Yu. A. Gracheva, Yu. K. Grishin, T. S. Kuznetsova, E. R. Milaeva, E. B. Averina, “Novel 8-arylidenetetrahydroquinazoline <i>N</i>-oxides: synthesis, photophysical properties and biological evaluation”, Mendeleev Commun., 2021, Volume 31, Issue 1,Pages <nobr>39

This article is cited in 2 papers

Communications

Novel 8-arylidenetetrahydroquinazoline N-oxides: synthesis, photophysical properties and biological evaluation

K. N. Sedenkova^ab, D. A. Vasilenko^a, D. V. Zverev^a, K. S. Sadovnikov^a, Yu. A. Gracheva^a, Yu. K. Grishin^a, T. S. Kuznetsova^a, E. R. Milaeva^ab, E. B. Averina^ab

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation

Abstract: New 8-arylidene-4-cyanotetrahydroquinazoline N-oxides were obtained via the condensation of readily available 4-cyanotetrahydroquinazoline N-oxides with aromatic aldehydes. Some of the synthesized compounds revealed fluorescent properties and moderate cytotoxic activity.

Keywords: tetrahydroquinazolines, condensation, cyanopyrimidine N-oxides, fluorescent properties, cytotoxic activity, quantum chemical calculations.

Language: English

DOI: 10.1016/j.mencom.2021.01.011

	*Supplementary materials:*
		Supplementary_data_1.pdf	2.7 Mb